欧米伽3对心脏病的保护作用

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2024年6月20日发(作者：)

美发现ω- 3脂肪酸对心脏病发作后

心脏损伤有保护作用

近期，在美国圣地亚哥举行的全美心脏病学会第64届年度科学会议上，全美心脏病

学会披露的一项对近期心脏病发幸存者的随机对照试验结果显示，服用ω- 3脂肪酸在进

一步降低炎症和防止心脏病心脏功能下降方面已经获得了最佳的治疗标准。

这项研究中，心脏病发作患者每天服用4克ω- 3脂肪酸处方药胶囊，服用6个月后，

与服用安慰剂的患者相比，心脏功能改善的更明显。数据显示，血液中ω- 3脂肪酸水平

有明显变化的患者获益最大。

部分原文如下：

Taking omega-3 fatty acids appeared to lower inflammation and guard against

further declines in heart function among recent heart attack survivors already

receiving optimal standard care, according to results from a randomized,

controlled trial.

Patients in the study taking 4 grams of prescription-only omega-3 fatty acid

capsules daily for six months after a heart attack were significantly more likely to

show improvements in heart function compared to patients taking a placebo.

Heart function was measured by an expansion of the left ventricular end-systolic

volume index. Patients taking omega-3 fatty acids also had significantly less

evidence of fibrosis -- a thickening or scarring of the areas of the heart remote

from the heart attack, which can develop when the surviving heart muscle works

harder and under high pressure to compensate for the damage to the heart. The

data suggests that patients who were able to mount a substantial change in levels

of omega-3 fatty acids in their blood derived the most benefit.

"Giving a high dose of omega-3 fatty acids soon after a heart attack appears

to improve cardiac structure and heart functioning above and beyond the

standard of care," said Raymond W. Kwong, M.D., M.P.H, director of cardiac

magnetic resonance imaging at Brigham and Women's Hospital in Boston and the

study's senior author. "Because this is a unique group of patients with remarkably

high adherence to [guideline-directed] treatments for acute myocardial infarction

already, we feel fairly confident that the benefits from this therapy are additive.

The implications of this study could be fairly large."

An estimated 720,000 Americans have heart attacks each year. After a heart

attack, the heart can remodel or reorganize itself to maintain or improve function.

In some cases, the heart may undergo adverse changes such as enlargement of

the heart, decreased pumping ability or added cardiac strain that can predispose

someone to heart failure and arrhythmias later in life.

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